Specific tumor-stroma interactions of EBV-positive Burkitt's lymphoma cells in the chick chorioallantoic membrane
نویسندگان
چکیده
منابع مشابه
Specific tumor-stroma interactions of EBV-positive Burkitt's lymphoma cells in the chick chorioallantoic membrane
BACKGROUND Burkitt's lymphoma (BL) is an aggressive Non-Hodgkin lymphoma. Epstein-Barr Virus (EBV) is able to transform B cells and is a causative infectious agent in BL. The precise role of EBV in lymphoma progression is still unclear. Most investigations have concentrated on cell autonomous functions of EBV in B cells. Functions of the local environment in BL progression have rarely been stud...
متن کاملEvaluating the Effects of Enrofloxacin on Angiogenesis Using the Chick Embryo Chorioallantoic Membrane Model
Objective- Because little information was available in the literature about the angiogenic property of enrofloxacin, this investigation was undertaken to evaluate this aspect using an in vivomodel. Design- Experimental study. Animals- Twenty fertile chicken eggs (Ross 308) with the average egg-weight of 55 ± 0.4 g were rand...
متن کاملThe chick embryo chorioallantoic membrane in the study of tumor angiogenesis.
The chick embryo chorioallantoic membrane (CAM) is commonly used as an experimental in vivo assay to study both angiogenesis and antiangiogenesis in response to tissues, cells or soluble factors. This article summarizes literature data about the use of the CAM in the study of tumor angiogenesis and particularly our experimental data concerning the study of angiogenesis in multiple myeloma and i...
متن کاملApplication of the Chick Embryo Chorioallantoic Membrane in Neurosurgery Disease
The chick embryo chorioallantoic membrane (CAM) is a highly vascularized extraembryonic membrane. Because of its ease of accessibility, extensive vascularization and immunodeficient environment, the CAM has been broadly used in the oncology, biology, pharmacy, and tissue regeneration research. The present review summarizes the application of the CAM in neurosurgery disease research. We focused ...
متن کاملIncreasing the purity, potency and specificity of ebv-specific T cells to improve the treatment of EBV-positive lymphoma
Results Although T2LP-specific EBVSTs could be generated from healthy-donors, we were unable to consistently generate EBVSTs with significant T2LP specificity from patients. We hypothesized that patient T cells were anergic to antigen expressed within tumors, and since IL-15 has been shown to rescue tolerant or anergic T cells, we replaced IL-4 with IL-15 (in combination with IL-7). This improv...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Vascular Cell
سال: 2012
ISSN: 2045-824X
DOI: 10.1186/2045-824x-4-3